LY3009120 ExtractorLY03009120 is a potent pan Raf inhibitor with IC50 of 44 nM, 31 47 nM, and 42 nM for A raf, B Raf, and C Raf in A375 cells, respectively. Phase 1.
Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM
It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR
it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex
modifications saved to the Audit Trail file
Gilteritinib(ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0
is mainly used for treating purulent skin infections
LY2409881 is a potent and selective IKK2 inhibitor with IC50 of 30 nM
modulates ion homeostasis and metabolism
(IC50 for canine influenza virus ranges from 0
Licochalcone A is an estrogenic flavanoid extracted from licorice root
Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent
6 nM in a cell-free assay